Respondus 4.0 Campus-wide runs in virtual machines with full versions of Windows 10 to 8.1. (Not Windows Emulators such as WINE and Codeweavers Crossover, or "VirtualApps" such as VMWare ThinApp).
Respondus 4.0 Campus-wide has been checked in various Windows VMs under VMWare (Mac and Windows), Parallels Desktop (Mac) and Oracle VirtualBox (Mac and Windows).
However, there are a few caveats when using Respondus 4.0 Campus-wide in a virtual machine:
1. The VM should run in a "Single Window" (or "Full Screen"). Any "shared desktop" such as VMWare Unity and Parallels Coherence should not be used.
2. "Shared folders" between the VM and host should be disabled, as the folders will appear as network folders, which is not supported in Respondus.