Respondus 4 provides tight integration with Blackboard Learn, D2L Brightspace, Instructure Canvas and Moodle 3-4.

For Respondus 4 compatibility with Moodle 4.0, please see this article.

Respondus 4 also supports the IMS QTI 1.2 specifications and recommendations, which makes it an ideal authoring system for QTI-compliant e-learning systems (e.g., Sakai, Itslearning, Perception by Questionmark).